F1-Adenosine Triphosphatase Displays Properties Characteristic of an Antigen Presentation Molecule for Vg9Vd2 T Cells
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CD1d-Restricted Antigen Presentation by Vg9Vd2-T Cells Requires Trogocytosis
CD1d-restricted invariant natural killer T cells (iNKT) constitute an important immunoregulatory T-cell subset that can be activated by the synthetic glycolipid a-galactosylceramide (a-GalCer) and play a dominant role in antitumor immunity. Clinical trials with a-GalCer–pulsed monocyte-derived dendritic cells (moDC) have shown anecdotal antitumor activity in advanced cancer. It was reported tha...
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